Thermo Fisher Scientific Cytokeratin 5/6 (Basal, Myoepithelial and Mesothelial Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT5.6/8275R)
Basal, myoepithelial 및 mesothelial 세포 마커로 사용되는 recombinant rabbit monoclonal 항체. IHC(P) 및 IHC(PFA)에서 검증됨. Human 시료 반응성, Protein A/G 정제, PBS(pH 7.4) 저장. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT5.6/8275R |
| Immunogen | Recombinant fragments of human Cytokeratin 5 (KRT5) and Cytokeratin 6 proteins (exact sequences are proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the keratin gene family. Type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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