Thermo Fisher Scientific MRE11 Monoclonal Antibody (44B12)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2 µg/mL

View 1 publication 1 publication

Immunoprecipitation (IP)

2 µg

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Product Specifications

Published species

Not Applicable

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

44B12

Immunogen

Recombinant human protein purified from E.coli (His-MRE11)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2538729

Product Specific Information

A suggested positive control for this product is HeLa cell lysate.

Target Information

MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3-5 exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.