Thermo Fisher Scientific Calmodulin 3 Polyclonal Antibody
Calmodulin 3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫트 반응성이 확인됨. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 단기, -20°C 장기 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment (amino acids 1–99 of Human Calmodulin 3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547454 |
Product Specific Information
- Recommended positive control: Mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%), Guinea pig (100%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Calcium-binding proteins (CaBP) are essential in calcium-mediated cellular signal transduction in the central nervous system. The CaBP family shares high similarity with calmodulin (CaM I) and can functionally substitute or augment CaM I activity.
CaBP7 contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
CaBP7 and 8 have a unique targeting mechanism among CaBPs that may contribute to differential Ca²⁺ sensing.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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