Thermo Fisher Scientific Colon carcinoma laminin binding protein Polyclonal Antibody
Colon carcinoma laminin binding protein을 인식하는 Rabbit polyclonal antibody로, WB 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. Lyophilized 형태, whole serum buffer에 보존. 연구용으로 세포 부착 및 암 관련 단백질 연구에 적합.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to aa region 50–100 of human 40S ribosomal protein SA conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: 40S ribosomal protein SA.
Target Information
Laminins are extracellular matrix glycoproteins and major noncollagenous constituents of basement membranes. They play roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminin effects are mediated through cell surface receptors, including integrins and non-integrin laminin-binding proteins.
This gene encodes a high-affinity, non-integrin laminin receptor 1 (also known as 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP), and p40 ribosome-associated protein). Its amino acid sequence is highly conserved, indicating a key biological function. Expression is elevated in colon carcinoma and lung cancer cells, correlating with invasive and metastatic phenotypes. Multiple pseudogene copies exist due to retropositional events. Two alternatively spliced transcript variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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