
Thermo Fisher Scientific Anoctamin-5 Polyclonal Antibody
Rabbit polyclonal antibody against Anoctamin-5 (ANO5). Validated for Western blot in mouse and rat samples. Supplied lyophilized, reconstitutable with DDW. High purity via antigen affinity chromatography. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)TKMEIPRTHQEYE, corresponding to amino acid residues 532–544 of mouse ANO5, 2nd intracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For long-term storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Ano5 does not exhibit calcium-activated chloride channel (CaCC) activity. The Ano5 gene encodes a member of the anoctamin family of transmembrane proteins. The Ano5 protein is likely a calcium-activated chloride channel. Mutations in the Ano5 gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described for Ano5.
Diseases associated with ANO5:
- Gnathodiaphyseal Dysplasia
- Miyoshi Muscular Dystrophy 3
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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