Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Monoclonal Antibody (2D1G11)
Phospho-4EBP1 (Ser65) 단백질을 인식하는 Mouse monoclonal antibody로, IHC, Flow Cytometry, ELISA 등에 사용 가능. Human 시료 반응성. Protein G 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1G11 |
| Immunogen | Synthesized peptide of human Phospho-4E-BP1 (Ser65) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787467 |
Product Specific Information
MA5-31844 has been tested in indirect ELISA.
Target Information
This gene encodes a member of the translation repressor protein family. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. Phosphorylation of this protein in response to signals such as UV irradiation and insulin signaling causes its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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