
Thermo Fisher Scientific LAMB3 Monoclonal Antibody (OTI1D3), TrueMAB
LAMB3 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1:150 희석 비율로 검증됨. 인간 시료에 반응하며, 동결 건조 형태로 제공. PBS 완충액에 8% 트레할로스 포함. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–315 of human LAMB3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LAMB3 encodes a laminin beta subunit that forms laminin-5 along with alpha and gamma subunits. Mutations in this gene are associated with epidermolysis bullosa junctional Herlitz type and generalized atrophic benign epidermolysis bullosa, both characterized by skin blistering. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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