Thermo Fisher Scientific C11orf84 Polyclonal Antibody
인간 C11orf84 단백질을 인식하는 Rabbit Polyclonal 항체입니다. IHC(P)에서 1:200–1:500 희석으로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공됩니다. SPIN1 관련 전사 조절 연구에 적합합니다.
- 카탈로그번호
- PA559077
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human C11orf84. Recombinant protein control fragment (Product #RP-97442) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.27 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638713 |
Product Specific Information
Immunogen sequence:
DCFEVTLKCE EGEDEEEAMV VAVIPRPEPM LRVTQQEKTP PPRPSPLEAG SDGCEEPKQQ VSWEQEFLVG SSPGGSGRAL CMVCGAEIRA PS
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 89%
Target Information
Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3, and SPIN4 (PubMed:29061846). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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