Thermo Fisher Scientific DTNB Monoclonal Antibody (OTI3C11)
DTNB 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF에 사용 가능. Human 시료 반응성, Affinity Chromatography 정제, PBS/BSA/glycerol buffer. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C11 |
| Immunogen | Full length human recombinant protein of DTNB produced in HEK239T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723099 |
Target Information
The DTNB gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC includes dystrophin and several integral and peripheral membrane proteins such as dystroglycans, sarcoglycans, syntrophins, and dystrobrevins (alpha and beta). This complex localizes to the sarcolemma and its disruption is linked to various forms of muscular dystrophy. Dystrobrevin beta interacts with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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