Thermo Fisher Scientific TERT Polyclonal Antibody
TERT 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. Mouse 시료 반응성이 있으며, 합성 펩타이드 면역원 기반으로 제작되었습니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- OST00355W-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TERT Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 10–60 of mouse TERT conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TERT.
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG.
The enzyme consists of a protein component with reverse transcriptase activity (encoded by TERT) and an RNA component serving as a template for the telomere repeat.
Telomerase expression is normally repressed in postnatal somatic cells, leading to progressive telomere shortening and cellular senescence.
Deregulation of telomerase may contribute to oncogenesis.
Studies in mouse suggest telomerase also aids chromosomal repair by synthesizing telomere repeats at double-stranded breaks.
Alternative splicing generates different isoforms of TERT, serving as a regulatory mechanism of telomerase activity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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