Thermo Fisher Scientific Cripto Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Cripto 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 사용. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TDGF1 (Accession P13385), corresponding to amino acid residues A96–L146 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900650 |
Product Specific Information
Antibody detects endogenous levels of total TDGF1.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling.
Cell-associated TDGF1 acts as a Nodal coreceptor in cis.
Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells.
TDGF1 is expressed both in embryonic stem (ES) cells and during early embryo development, and in adults it is reactivated in a wide range of epithelial cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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