Thermo Fisher Scientific IL-2 Recombinant Rabbit Monoclonal Antibody (257)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Mouse IL-2 / Interleukin-2.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine essential for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7).

Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mode for precise gene expression. Targeted disruption of an IL-2-like gene in mice leads to ulcerative colitis-like disease, indicating its crucial role in immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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