Thermo Fisher Scientific PDE1A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250-1:500

-

Immunoprecipitation (IP)

1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE1A,uniProtId:P54750-1,ncbiNodeId:9606,antigenRange:1,antigenLength:535,antigenImageFileName:PA1-31124_PDE1A_P54750-1_Rabbit.svg,antigenImageFileNamePDP:PA1-31124_PDE1A_P54750-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.65 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris glycine, pH 7.4-7.9, with 30% glycerol, 0.5% BSA

Contains

0.02% Sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2162896

Product Specific Information

Recommended positive controls: Rat testis.

Target Information

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1)that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.