Thermo Fisher Scientific PDE1A Polyclonal Antibody
PDE1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 보관 또는 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250–1:500 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine, pH 7.4–7.9, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2162896 |
Product Specific Information
- Recommended positive control: Rat testis
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide concentrations by hydrolyzing cAMP and/or cGMP to their respective nucleoside 5′-monophosphates, playing a key role in signal transduction. Members of the PDE1 family, including PDE1A, are Ca(2+)/calmodulin-dependent enzymes activated by calmodulin in the presence of Ca(2+).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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