Thermo Fisher Scientific Heme Oxygenase-1 Monoclonal Antibody (GTS-1)
Heme Oxygenase-1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Lyophilized 형태로 제공됩니다. 단백질 A로 정제되었으며 보존제는 포함되어 있지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–10 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GTS-1 |
| Immunogen | Microsomal fraction of transformed mouse T-cell transfected with rat heme oxygenase-1 (WR19LrHO-1) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | No preservative |
| Storage Conditions | 2–8°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 50 µL of distilled water; final concentration will be 2 mg/mL.
If further dilution is needed, dilute this stock with 10 mM PBS, pH 7.4 + 1% BSA immediately before use.
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules biliverdin and carbon monoxide.
HO consists of two homologous isozymes: an inducible HO-1 and a constitutively expressed HO-2.
HO-1 is induced by various stimuli including oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock.
The increase in expression of HO-1 is considered a cellular defense mechanism against oxidative stress since elevated HO could generate more bilirubin, an antioxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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