Thermo Fisher Scientific NFRKB Polyclonal Antibody
Rabbit polyclonal antibody specific to human NFRKB. Validated for IHC (P) and ICC/IF applications. Antigen affinity purified and supplied as a liquid in PBS with glycerol. Suitable for research use in immune cell and transcription factor studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NFRKB. Recombinant protein control fragment (Product # RP-89400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644649 |
Product Specific Information
Immunogen sequence:
KSSSGVLLVS SPTMPHLGTM LSPASSQTAP SSQAAARVVS HSGSAGLSQV RVVAQPSLPA VPQQSGGPAQ TLPQMPAGPQ IRVPATATQT KVVPQTVMAT VPVKAQTTAA TV
Antigen sequence identity:
- Mouse: 87%
- Rat: 87%
Target Information
NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that binds a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2Rα) gene. NFRKB appears to function as a transcription factor central to immune cell development. It has been identified as an amplified gene in several cases of acute myeloid leukemia, and partial deletion of its chromosomal region has been associated with combined cellular immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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