Thermo Fisher Scientific Tapasin Polyclonal Antibody
Human Tapasin 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태로 제공. PBS 및 글리세롤 버퍼에 보존되어 안정적이며, 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Tapasin. Recombinant protein control fragment (Product #RP-90110) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648216 |
Product Specific Information
Immunogen sequence:
QEGTYLATIH LPYLQGQVTL ELAVYKPPKV SLMPATLARA APGEAPPELL CLVSHFYPSG GLEVEWELRG GPGGRSQKAE GQRWLSALRH HSDGSVSLSG HLQPPPVTTE QHGARYACRI HHPS
- Highest antigen sequence identity to orthologs:
- Mouse: 73%
- Rat: 77%
Target Information
This gene encodes a transmembrane glycoprotein that mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP). This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may bind to a single TAP molecule.
The protein contains a C-terminal double-lysine motif (KKKAE) that maintains membrane proteins in the endoplasmic reticulum. The gene lies within the major histocompatibility complex on chromosome 6, and alternative splicing results in three transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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