Thermo Fisher Scientific CCDC79 Polyclonal Antibody
Rabbit polyclonal antibody against human CCDC79 protein. Validated for ICC/IF applications. Affinity purified and supplied in PBS with 40% glycerol. Recommended dilution 0.25–2 µg/mL. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 431–524) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091920 |
Product Specific Information
Immunogen sequence:
NYQDNISSMN ISIQNTWKHL HADRIGRGSK AEDEDKSHSR QLQSYKSHGV MSKACTNDDQ MKTPLKSANP VHACYRESEQ NKTLYKAKSS CNQN
Antigen sequence identity:
- Mouse: 46%
- Rat: 49%
Target Information
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which mediates attachment of telomeric DNA to the inner nuclear membrane and promotes telomere cap exchange. During prophase, the complex facilitates release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 likely mediates association with the shelterin/telosome complex via interaction with TERF1, promoting telomeric DNA attachment. It also promotes telomere association with the nuclear envelope, deposition of the SUN-KASH/LINC complex, and recruitment of cohesin to telomeres for structural rigidity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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