Thermo Fisher Scientific CCDC123 Polyclonal Antibody
CCDC123 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 Western blot에 적합. 합성 펩타이드 항원을 사용해 제작되었으며, 액상 형태로 0.5 mg/mL 농도 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of Human CEP89 (aa 41–90) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884787 |
Product Specific Information
- Immunogen sequence: PNPSPERPRS ALAAAILATT LTGRTVAIPQ PRQRSRSESD VSSVEQDSFI
- Storage guidance:
- Short term: 2–8°C (up to 1 week)
- Long term: -20°C (store in small aliquots to prevent freeze-thaw cycles)
- Predicted homology:
- Guinea Pig: 85%
- Horse: 91%
- Human: 100%
- Mouse: 92%
- Rat: 92%
Target Information
CCDC123 (also known as CEP123 or CEP89) is involved in primary ciliogenesis and mitochondrial metabolism, potentially modulating complex IV activity. It localizes to the distal appendages of the mother centriole in a cell cycle-dependent manner, decreasing during mitosis. Depletion of CEP123 can cause defects in ciliary vesicle formation and inhibit vesicle development at the distal end of the mother centriole. It may regulate membrane recruitment to the centrosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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