Thermo Fisher Scientific Phospho-NFkB-p100 (Ser866) Recombinant Rabbit Monoclonal Antibody (1J7E2)
Phospho-NFkB-p100 (Ser866) 단백질을 검출하는 재조합 토끼 단클론 항체. Western blot과 ELISA에 적합하며 높은 특이성과 재현성을 제공. HEK293 세포에서 발현되고 Protein A로 정제된 고순도 항체. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1J7E2 |
| Immunogen | A synthetic phosphorylated peptide around S866 of human Phospho-NF-kB2-S866 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
- Immunogen Sequence: EDSAY
Target Information
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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