Thermo Fisher Scientific ApoCI Polyclonal Antibody, HRP

Applications and Tested Dilution

Product Specifications

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins.

The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver, activated when monocytes differentiate into macrophages.
The apoC-II gene, also on chromosome 19q13.2, encodes a 79 amino acid single-chain protein that acts as a cofactor for lipoprotein lipase activation, facilitating triglyceride hydrolysis and fatty acid transfer.
The apoC-III gene (chromosome 11q23) encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein and hepatic lipases.
The apoC-IV gene (chromosome 19q13.2) encodes a 127 amino acid protein primarily expressed in the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.