Thermo Fisher Scientific HCG-beta Recombinant Rabbit Monoclonal Antibody (HCGb, 1996R)
Recombinant rabbit monoclonal antibody against hCG beta subunit. Validated for IHC (Paraffin). High specificity to human hCGβ, expressed in HEK293 cells. Supplied as liquid, 200 µg/mL, purified by Protein A/G. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC-P): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HCGb, 1996R |
| Immunogen | Recombinant full-length hCG beta protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- IHC (PFA-fixed): Incubate antibody for 30 minutes at room temperature.
- For staining of formalin-fixed tissues: heat tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
hCG beta is the beta chain of human chorionic gonadotropin (hCG), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10–12 days after conception.
hCG consists of alpha and beta subunits that are non-covalently associated. The alpha subunit resembles that of FSH, LH, and TSH, while the beta subunit confers biological specificity.
During early pregnancy, hCG stimulates the corpus luteum to produce progesterone, maintaining the endometrium. hCG levels rise sharply during pregnancy and are minimal in non-pregnant individuals.
Diseases associated with hCG dysfunction include gestational trophoblastic tumor and hydatidiform mole.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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