Thermo Fisher Scientific MRP1 Recombinant Rabbit Monoclonal Antibody (3W1Y4)
MRP1 인간 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot과 ELISA에 적합하며, 높은 특이성과 재현성을 제공. HEK293 세포에서 발현된 단백질 A 정제 항체로 연구용에 최적화됨.
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Thermo Fisher Scientific MRP1 Recombinant Rabbit Monoclonal Antibody (3W1Y4)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3W1Y4 |
| Immunogen | Recombinant protein of human MRP1/ABCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. It functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. It also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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