Thermo Fisher Scientific IL-2 Monoclonal Antibody (JES6-5H4), eBioscience

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

Immunohistochemistry (IHC)

Assay-Dependent

-

Flow Cytometry (Flow)

Assay-Dependent

View 6 publications 6 publications

ELISA (ELISA)

Assay-Dependent

-

Immunoprecipitation (IP)

Assay-Dependent

-

Product Specifications

Species Reactivity

Mouse

Published species

Human, Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

JES6-5H4

Immunogen

Rec. Mouse IL-2

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Alexa Fluor 488
• APC
• APC-eFluor 780
• Biotin
• Brilliant UV 737
• eFluor 450
• FITC
• Functional Grade
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-Cyanine5.5
• Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10597277

Product Specific Information

Description: BMS180 (JES6-5H4) is raised against recombinant full length IL-2 of mouse origin and recommended for detection of recombinant and native IL-2 of mouse origin by IP,ELISA, FC, WB. The antibody was purified from tissue culture supernatant by protein G column chromatography.

Applications Tested: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blotting.

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.