Thermo Fisher Scientific CD105 Polyclonal Antibody
CD105(Endoglin)에 특이적인 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA에 사용 가능. Human Endoglin/CD105 단백질을 면역원으로 제작. 보존제가 포함되지 않아 사용 전 NaN3 첨가 권장. 인간 혈관 내피세포 연구 및 종양 혈관생성 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 | - |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 | - |
| ELISA | 1:5,000–1:10,000 | View 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Published species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Endoglin/CD105 Protein (Met1–Gly586) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787881 |
Product Specific Information
- This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05–0.1%) to prevent contamination.
- This antibody specifically recognizes Human Endoglin/CD105.
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, making it a proliferation-associated endothelial marker.
CD105 binds TGF-β1 and TGF-β3 with high affinity but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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