Thermo Fisher Scientific EMAP II Polyclonal Antibody
EMAP II 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 생쥐, 초파리 등과 반응하며 항원 친화 크로마토그래피로 정제됨. 4°C 또는 -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry - Free Floating (IHC (Free)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 117–312 of Human AIMP1 (EMAP II) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547780 |
Product Specific Information
- Recommended positive controls: HeLa, Jurkat, NIH-3T3, JC, BCL-1
- Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (83%), Xenopus laevis (86%), Pig (94%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a cytokine specifically induced by apoptosis, involved in the regulation of angiogenesis, inflammation, and wound healing. Its release sensitizes tumor-associated vasculature to tumor necrosis factor. The precursor protein is identical to the p43 subunit of the multi-tRNA synthetase complex and modulates aminoacylation activity in normal cells. Proteolytic cleavage in tumor cells stimulates inflammatory responses. Multiple transcript variants and a pseudogene on chromosome 20 have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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