Thermo Fisher Scientific XRCC3 Monoclonal Antibody (OTI5B11), TrueMAB
인간 XRCC3 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. 정제된 액상 형태이며, PBS/BSA/glycerol 완충액에 보관됩니다. DNA 손상 복구 연구용으로 사용되며, -20°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–235 of human XRCC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The XRCC3 gene encodes a member of the RecA/Rad51-related protein family involved in homologous recombination to maintain chromosome stability and repair DNA damage. It complements the Chinese hamster irs1SF repair-deficient mutant, which is hypersensitive to DNA-damaging agents and chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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