Thermo Fisher Scientific KAP1 (TRIM28) Monoclonal Antibody (OTI5E10)
KAP1(TRIM28) 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. Human 시료 반응성. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E10 |
| Immunogen | Full length human recombinant protein of human TRIM28 (NP_005753) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The KRAB (Kruppel-associated box) domain is about 45 amino acids in length and is a transcriptional repression domain found in numerous transcription factors. Over 220 KRAB-zinc finger protein (KRAB-ZFP) genes have been identified in the human genome. These proteins repress transcription via specific interactions with KAP-1 (KRAB-associated protein 1).
KAP-1 is an 835 amino acid polypeptide containing a RING finger, B boxes, and a PHD finger. It forms complexes with KRAB-domain transcription factors to enhance transcriptional repression efficiency. KAP-1 also interacts directly with HP1 (heterochromatin protein 1) and KRAZ1 (Kruppel-associated box-containing zinc finger protein 1), targeting KRAZ1 to centromeric heterochromatin regions containing HP1α to regulate transcriptional repression. Mutant KAP-1 unable to bind HP1 results in random KRAZ1 distribution and strong transcriptional activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific KAP1 (TRIM28) Monoclonal Antibody (OTI8B12)
676,500원
Thermo Fisher Scientific
Thermo Fisher Scientific KAP1 (TRIM28) Monoclonal Antibody (OTI9F4)
676,500원
Thermo Fisher Scientific
Thermo Fisher Scientific KAP1 (TRIM28) Monoclonal Antibody (OTI5E10)
676,500원
Thermo Fisher Scientific
Thermo Fisher Scientific KAP1 (TRIM28) Monoclonal Antibody (OTI7A4)
676,500원
Thermo Fisher Scientific
Thermo Fisher Scientific p38 (MAPK14) Monoclonal Antibody (OTI7H6)
676,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|