Thermo Fisher Scientific ITPA Polyclonal Antibody
ITPA 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol로 안정화. 인간 ITPA 단백질에 특이적이며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ITPA. Recombinant protein control fragment (Product #RP-91737) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642824 |
Product Specific Information
Immunogen sequence:
GFEDKSAYAL CTFALSTGDP SQPVRLFRGR TSGRIVAPRG CQDFGWDPCF QPDGYEQTYA EMPKAEKNAV SHRFRALLEL QEYFGSLAA
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 83%
Target Information
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP), 2′-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP), and xanthosine 5′-triphosphate (XTP) to their respective monophosphate derivatives.
The enzyme does not distinguish between deoxy- and ribose forms. It likely excludes non-canonical purines from RNA and DNA precursor pools, preventing their incorporation and avoiding chromosomal lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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