Thermo Fisher Scientific DUSP16 Polyclonal Antibody
DUSP16 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체로, Bovine, Human, Mouse, Non-human primate에 반응. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 600–650 of human DUSP16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2540667 |
Target Information
Dual-specificity phosphatases (DUSPs) are a heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily.
DUSPs can dephosphorylate both tyrosine and serine/threonine residues.
DUSP16 belongs to the MAPK phosphatases (MKPs) class, which dephosphorylates MAPK proteins ERK, JNK, and p38 with distinct specificity.
MKPs contain a conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain.
MAPK activation cascades mediate various processes such as cellular proliferation, apoptosis, differentiation, and stress responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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