Thermo Fisher Scientific HSP90AB1 (HSP90) Monoclonal Antibody (OTI4C10), TrueMAB
HSP90AB1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human, Mouse, Rat, Dog에 반응. Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol buffer에 보관. 세포 스트레스 및 단백질 접힘 연구용.
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Applications
- Western Blot (WB): 1:2,000
Publications
- Miscellaneous PubMed (Misc): N/A
- View 9 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C10 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human HSP90AB1 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions but is also one of the most abundant cellular proteins under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones with key roles in:
- Signal transduction
- Protein folding and degradation
- Morphologic evolution
HSP90 associates with cochaperones and assists in folding newly synthesized proteins or refolding denatured proteins after stress. It interacts with intracellular proteins such as steroid receptors, actin, tubulin, aryl hydrocarbon receptor, and certain kinases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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