Thermo Fisher Scientific Cathepsin O Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 Cathepsin O 단백질 검출에 사용됩니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human Cathepsin O |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719469 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The cathepsin family of proteolytic enzymes includes several classes of proteases.
- Cysteine proteases: Cathepsins B, L, H, K, S, and O
- Aspartyl proteases: Cathepsins D and E
- Serine protease: Cathepsin G
Most cathepsins are lysosomal enzymes involved in cellular metabolism, including peptide biosynthesis and protein degradation.
Cathepsin O maintains structural features typical of cysteine proteinases, including the active site cysteine residue that forms a covalent intermediate during peptide hydrolysis. It functions as an endoproteinase potentially involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney, and placenta, with lower expression in thymus and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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