Thermo Fisher Scientific HSPB8 Polyclonal Antibody
Human HSPB8 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 적합하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 4°C 또는 -20°C에서 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human HSPB8/Cryac |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788375 |
Product Specific Information
This antibody has specificity for Human HSPB8/Cryac.
Target Information
The HSPB8 gene encodes a small heat-shock protein containing a conserved alpha-crystallin domain at the C-terminal region. Its expression is induced by estrogen in estrogen receptor-positive breast cancer cells. HSPB8 functions as a chaperone in association with Bag3, promoting macroautophagy. It is involved in regulating cell proliferation, apoptosis, and carcinogenesis. Mutations in this gene are associated with neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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