Thermo Fisher Scientific TCEB1 Polyclonal Antibody
TCEB1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA 등에 사용 가능하며 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C 보관 시 안정적입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–112 of human TCEB1 (NP_001191791.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.54 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913742 |
Product Specific Information
Positive test controls include Jurkat, PC-3, MCF7, HepG2, Mouse liver, Mouse lung, Mouse testis, Mouse brain, Rat brain.
The target is usually found in the following locations: Nucleus.
Immunogen sequence:
MDGEEKTYGG CEGPDAMYVK LISSDGHEFI VKREHALTSG TIKAMLSGPG QFAENETNEV NFREIPSHVL SKVCMYFTYK VRYTNSSTEI PEFPIAPEIA LELLMAANFL DCTarget Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex composed of elongins A/A2, B, and C.
This complex activates elongation by RNA polymerase II by suppressing transient pausing during transcription.
Elongin A functions as the transcriptionally active component, while elongins B and C serve as regulatory subunits.
Elongin A2 is specifically expressed in the testis and forms a stable complex with elongins B and C.
The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, thereby inhibiting transcription elongation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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