Thermo Fisher Scientific Human Osteopontin Synthetic Peptide
인간 Osteopontin의 N-말단 18개 아미노산 서열을 기반으로 한 합성 펩타이드. Western blot에서 PA5-34579 항체의 블로킹 펩타이드로 사용 가능. 200 µg/mL 농도의 액상 형태로 제공되며, PBS(pH 7.2)에 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP1622
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human Osteopontin Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of SPP1.
PEP-1622 can be used as a blocking peptide with polyclonal antibody PA5-34579.
For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Target Information
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease, and transformation.
Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties.
Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and a novel substrate for plasmin and cathepsin D.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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