Thermo Fisher Scientific ATRIP Monoclonal Antibody (OTI4A8), TrueMAB
ATRIP 단백질을 인식하는 마우스 단클론 항체로 Western blot과 ICC/IF에 적합. 정제된 무보존제 항체이며, 동결건조 형태로 제공. DNA 손상 반응 연구 및 ATR 경로 분석에 유용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 42–309 of human ATRIP produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ATRIP is an 86 kDa protein phosphorylated by ATR, regulating ATR expression and functioning as an essential component of the DNA damage checkpoint pathway. It localizes to intranuclear foci following DNA damage or replication inhibition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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