Thermo Fisher Scientific SSTR5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2,000

-

Immunocytochemistry (ICC/IF)

1:5,000

-

Product Specifications

Species Reactivity

Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the C-terminal amino acids Q(344)ATLPTRSCEANGLMQTSRI(363) of SSTR5 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SSTR5,uniProtId:P30938-1,ncbiNodeId:10114,antigenRange:344-363,antigenLength:363,antigenImageFileName:PA3-209_SSTR5_P30938-1_Rabbit.svg,antigenImageFileNamePDP:PA3-209_SSTR5_P30938-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10984599

Product Specific Information

PA3-209 detects SSTR5 in rat and mouse samples.

PA3-209 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures.

The PA3-209 immunogen is a synthetic peptide corresponding to the C-terminal amino acids Q(344)ATLPTRSCEANGLMQTSRI(363) of SSTR5

Target Information

Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.