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Thermo Fisher Scientific Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R)
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Thermo Fisher Scientific Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R)

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Calretinin(CALB2) 단백질을 인식하는 재조합 토끼 단클론 항체로, 중피종 표지자 연구에 적합. Western blot 및 IHC 등 다양한 응용 가능. 인간 시료 반응성, HEK293 발현 시스템 기반. 24개월 안정성 보유, 단백질 A 정제.

카탈로그번호
794-RBM12-P1
판매단위
pk
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마지막 업데이트 2025. 08. 03. 오후 12:07
Thermo Fisher Scientific 794-RBM12-P1 Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R) 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R)

Thermo Fisher Scientific Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R)

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 1–2 µg/mL
Peptide Array (Array) Assay-dependent
Immunoelectrophoresis (IE) Assay-dependent

Product Specifications

Specification Description
Species Reactivity Human
Host / Isotype Rabbit / IgG
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone CALB2/7029R
Immunogen Recombinant human Calretinin (Calbindin 2) protein fragment (around aa23–242)
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A
Storage Buffer PBS with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Antibody stability: 24 months
  • Positive control: Human brain, testis, or mesothelioma tissue
  • Cellular localization: Cytoplasm, nucleus
  • Specificity: Recognizes a ~29 kDa protein identified as Calretinin (Calbindin 2), a vitamin D-dependent calcium-binding protein involved in calcium signaling.
  • Diagnostic relevance: Useful for differentiating mesothelioma from adenocarcinomas of the lung, and adrenal cortical neoplasms from pheochromocytomas.

Target Information

Calretinin is encoded by the CALB2 gene on chromosome 16. It belongs to the troponin C superfamily and contains six EF-hand structural motifs that enable calcium binding. Calretinin functions in calcium signaling, buffering, and neuronal excitability modulation. It is expressed in mesothelium, mast cells, neural cells, hair follicles, and fat cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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