
Thermo Fisher Scientific NR2E3 Monoclonal Antibody (2A12)
Thermo Fisher Scientific의 NR2E3 단클론 항체(2A12)는 인간 NR2E3 단백질을 인식하며 Western blot 및 ELISA에 적합합니다. GST 태그가 결합된 재조합 단백질로부터 제조되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00010002-M01
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A12 |
| Immunogen | NR2E3 (AAH41421, 1–322 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA QVHLDSMESN TESRPESLVA PPAPAGRSPR GPTPMSAARA LGHHFMASLI TAETCAKLEP EDADENIDVT SNDPEFPSSP YSSSSPCGLD SIHETSARLL FMAVKWAKNL PVFSSLPFRD QVILLEEAWS ELFLLGAIQW SLPLDSCPLL APPEASAAGG AQGRLTLASM ETRVLQETIS RFRALAVDPT EFACMKALVL FKPETRGLKD PEHVEALQDQ SQVMLSQHSK AHHPSQPVRF GKLLLLLPSL RFITAERIEL LFFRKTIGNT PMEKLLCDMF KN
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It plays a role in determining photoreceptor phenotype during human retinogenesis.
In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration.
A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte.
Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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