Thermo Fisher Scientific NUP98 Polyclonal Antibody
인간 NUP98 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액으로 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA5111725
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NUP98 Polyclonal Antibody
Thermo Fisher Scientific NUP98 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NUP98. Recombinant protein control fragment (Product #RP-108019). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2857135 |
Product Specific Information
Immunogen sequence:
NTSDSDRYAC SPLPSYLEGS GCVIAEEQNS QTPLRDVCFH LLKLYSDRHY DLNQLLEPRS ITADPLDYRL SWHLWEVLRA LNYTHLSAQC EGVLQ
Target Information
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both localized to the nucleoplasmic side of the NPC.
Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates.
The human gene has been shown to fuse to several genes following chromosome translocations in AML and T-ALL. This gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor region associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and various cancers.
Alternative splicing results in several transcript variants; not all have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-111725_NUP98_P52948-1_Rabbit.svg, PA5-111725_NUP98_P52948-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.