Thermo Fisher Scientific STAT2 Monoclonal Antibody (2E9)
STAT2 단백질을 인식하는 Mouse monoclonal antibody (Clone 2E9). Western blot과 ELISA에 적합하며, 인간 시료에 반응. PBS buffer 내 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E9 |
| Immunogen | STAT2 (AAH51284, 742–851 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KAGLDLGPEL ESVLESTLEP VIEPTLCMVS QTVPEPDQGP VSQPVPEPDL PCDLRHLNTE PMEIFRNCVK IEEIMPNGDP LLAGQNTVDE VYVSRPSHFY TDGPLMPSDF
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and form homo- or heterodimers that translocate to the nucleus to act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and IFN regulatory factor p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability.
Transcription adaptor P300/CBP (EP300/CREBBP) interacts with STAT2 and may be involved in the inhibition of IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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