Thermo Fisher Scientific F7 Polyclonal Antibody, MaxPab
인간 F7 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 in situ PLA에 사용 가능. Affinity chromatography로 정제되었으며, PBS(pH 7.4) 용액 형태로 제공. 보존제 무첨가, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| in situ PLA (PLA) | 1:1,200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | F7 (NP_062562.1, 1 a.a. – approximately 444 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MVSQALRLLC LLLGLQGCLA AVFVTQEEAH GVLHRRRRAN AFLEELRPGS LERECKEEQC SFEEAREIFK DAERTKLFWI SYSDGDQCAS SPCQNGGSCK DQLQSYICFC LPAFEGRNCE THKDDQLICV NENGGCEQYC SDHTGTKRSC RCHEGYSLLA DGVSCTPTVE YPCGKIPILE KRNASKPQGR IVGGKVCPKG ECPWQVLLLV NGAQLCGGTL INTIWVVSAA HCFDKIKNWR NLIAVLGEHD LSEHDGDEQS RRVAQVIIPS TYVPGTTNHD IALLRLHQPV VLTDHVVPLC LPERTFSERT LAFVRFSLVS GWGQLLDRGA TALELMVLNV PRLMTQDCLQ QSRKVGDSPN ITEYMFCAGY SDGSKDSCKG DSGGPHATHY RGTWYLTGIV SWGQGCATVG HFGVYTRVSQ YIEWLQKLMR SEPRPGVLLR APFP
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. It circulates in the blood as a zymogen and is activated by factor IXa, Xa, XIIa, or thrombin. Upon activation, it forms a heavy chain (catalytic domain) and a light chain (two EGF-like domains) linked by a disulfide bond. In the presence of factor III and calcium ions, activated factor VII further activates the coagulation cascade by converting factor IX to IXa and/or factor X to Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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