Thermo Fisher Scientific Phospho-Stat6 (Tyr641) Recombinant Rabbit Monoclonal Antibody (Stat6Y641-G12), PE
PE 형광 표지된 재조합 Rabbit Monoclonal 항체로, 인간 및 생쥐 Stat6 Tyr641 인산화 단백질 검출에 적합합니다. Flow Cytometry에 최적화되어 있으며, 고순도 Protein A/G 정제 및 안정적인 PBS-BSA buffer로 제공됩니다. 연구용 전용 제품입니다.
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- MA537225
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- pk
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Stat6Y641-G12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897159 |
Additional Formats
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL-13. STAT6-deficient (Stat6-/-) cells show impaired IL-4-mediated functions, including Th2 helper T-cell differentiation, expression of surface markers, T-cell proliferation, and immunoglobulin class switching to IgE. STAT6 mRNA is expressed in multiple tissues, including lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta. STAT6 plays a critical role in Th2 immune response and IL-4-mediated biological processes, existing in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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