Thermo Fisher Scientific STEAP4 Polyclonal Antibody
인간 STEAP4 단백질을 인식하는 토끼 폴리클로날 항체로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS(40% 글리세롤) 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장. 전립선암 연구 등 STEAP4 관련 연구에 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human STEAP4. Recombinant protein control fragment (Product #RP-108061) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663633 |
Product Specific Information
- Immunogen sequence: IRYYVRWRLGN LTVTQAILKK ENPFSTSSAW LSD
- Highest antigen sequence identity: Mouse 65%, Rat 71%
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to STEAP2 and STEAP3, STEAP4 promotes both iron and copper reduction. It is highly expressed in placenta, lung, heart, and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 significantly increases cell growth and colony formation, suggesting a role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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