Thermo Fisher Scientific PDE8B Polyclonal Antibody
Rabbit polyclonal antibody against PDE8B for WB, IHC, and IP applications. Recognizes human PDE8B peptide. Supplied as liquid, 0.75 mg/mL concentration. Ideal for research use with rat testis and heart as positive controls.
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Thermo Fisher Scientific PDE8B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunoprecipitation (IP) | 1:250 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2283631 |
Product Specific Information
Recommended positive controls: Rat testis and heart.
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5′,3′-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5′-monophosphates. Mammalian PDEs are grouped into several families based on substrate affinities, inhibitor sensitivities, regulatory modes, and amino acid sequence homologies. The PDE8 family includes high-affinity cAMP-specific, IBMX-insensitive PDEs such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that contributes to distinct regulatory properties.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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