Thermo Fisher Scientific VAV3 Recombinant Rabbit Monoclonal Antibody (9A10D8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

9A10D8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human VAV3 (Q9UKW4). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VAV3,uniProtId:Q9UKW4-1,ncbiNodeId:9606,antigenRange:700-800,antigenLength:847,antigenImageFileName:MA5-42927_VAV3_Q9UKW4-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42927_VAV3_Q9UKW4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912068

Product Specific Information

Positive test controls include: Jurkat, Mouse brain.

Immunogen sequence: TKESGEYAIS IKYNNEAKHI KILTRDGFFH IAENRKFKSL MELVEYYKHH SLKEGFRTLD TTLQFPYKEP EHSAGQRGNR AGNSLLSPKV LGIAIARYDF C

Target Information

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.