Thermo Fisher Scientific RPL29 Polyclonal Antibody
Thermo Fisher Scientific의 RPL29 Polyclonal Antibody는 인간 RPL29 단백질을 인식하는 고품질 rabbit IgG 항체입니다. WB, IHC, ICC/IF에 적합하며, 높은 특이성과 다양한 종에서 예측 반응성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–159 of Human RPL29 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545021 |
Product Specific Information
- Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH
- Predicted reactivity: Mouse (84%), Rat (85%), Pig (93%), Rhesus Monkey (97%), Chimpanzee (96%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of this family show distinct substrate specificities, tissue distribution, subcellular localization, and inducibility by extracellular stimuli.
This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. It is evenly distributed in both cytoplasm and nucleus, widely expressed in various tissues, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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