Thermo Fisher Scientific ZNF687 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZNF687. Recombinant protein control fragment (Product #RP-93581). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZNF687,uniProtId:Q8N1G0-1,ncbiNodeId:9606,antigenRange:887-956,antigenLength:1237,antigenImageFileName:PA5-54347_ZNF687_Q8N1G0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54347_ZNF687_Q8N1G0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2650286

Product Specific Information

Immunogen sequence: EETAGKGAGG ALLTPKTEPE ELAVSQGGAA PATEESSSSS EEEEVPSSPE PPRPAKRPRR ELGSKGLKGG

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.

Target Information

The zinc finger protein 687 (ZNF687) was initially identified as a translocation partner gene with RUNX1 in patients with acute myeloid leukemia (AML). Little is known of the function of the ZNF687 protein, but it has been shown to weakly interact with the Ring1/Rnf2 RING finger protein member of the Polycomb group of proteins, suggesting it may be involved in the chromatin-modifying complexes essential for embryonic development and stem cell renewal. Other evidence suggests that ZNF687 may be part of a transcriptional network that also includes ZNF592 and ZMYMD8.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.