Thermo Fisher Scientific Phospho-FGFR1 (Tyr776) Polyclonal Antibody
FGFR1 Tyr776 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB·ELISA·IP에 적합. 인간 및 랫트 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 안정적이며 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-FGFR1 (Tyr776) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 640–690 on human FGFR1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family (FGFR1–4), which are membrane-spanning tyrosine kinases serving as high-affinity receptors for 17 growth factors (FGF1–17). The FGF receptor family is crucial in mesoderm induction, patterning, cell growth, migration, organ formation, and bone development.
FGFR1 undergoes alternative splicing, producing multiple variants expressed differently during embryogenesis and in adult tissues. Mutations or defects in FGFR1 are linked to diseases such as Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, and other congenital disorders. Chromosomal aberrations involving FGFR1 are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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