Thermo Fisher Scientific Phospho-LKB1 (Ser428) Polyclonal Antibody
인간 LKB1 단백질의 Ser428 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등에 적합. 고순도 액상 형태로 제공되며, -20°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of Ser428 (R-L-SP-A-C) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554967 |
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family. LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways. It is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK. Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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