Thermo Fisher Scientific BIRC3 Monoclonal Antibody (OTI1D12), TrueMAB
인간 BIRC3 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 Immunocytochemistry에 최적화됨. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. PBS/BSA/glycerol buffer로 안정화된 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of human BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases. It inhibits apoptosis induced by serum deprivation but not that caused by menadione exposure. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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